preamble:
  summary: Simple custom pipeline
  input_reference_genome: hg38/genomes/GRCh38-hg38

annotators:
- effect_annotator:
    gene_models: hg38/gene_models/MANE/1.5
    attributes:
    - worst_effect
    - genes

- position_score_annotator:
    resource_id: hg38/scores/phyloP7way

- normalize_allele_annotator

- allele_score_annotator:
    resource_id: hg38/scores/ClinVar_20251019
    input_annotatable: normalized_allele
    attributes:
    - CLNSIG
    - CLNDN