.. GPF documentation master file, created by sphinx-quickstart on Thu Dec 18 10:54:50 2025. You can adapt this file completely to your liking, but it should at least contain the root `toctree` directive. GPF: Genotypes and Phenotypes in Families documentation ======================================================= GPF (Genotypes and Phenotypes in Families) is an open-source platform that manages genotypes and phenotypes derived from collections of families. The GPF interface allows interactive exploration of genetic variants, enrichment analysis for de novo mutations, and phenotype/genotype association tools. In addition, GPF allows researchers to share their data securely with the broader scientific community. See the `Analyzing the large and complex SFARI autism cohort data using the Genotypes and Phenotypes in Families (GPF) platform `_ for a detailed description. GPF is an open-source project available at `GitHub `_ developed by Iossifov's group at CSHL and Seqpipe Ltd. GPF is deployed at the Simons Foundation (https://gpf.sfari.org), providing protected access to comprehensive genotypic and phenotypic data for the SSC, SPARK, and related datasets. Tutorial videos --------------- - short: https://youtu.be/6G_woic72Qk - long: https://youtu.be/-4-bF08JiR8 GPF Documentation ----------------- .. toctree:: :maxdepth: 3 user_interface/gpf_user_interface administration/gpf_administration development/gpf_development